Calculate log lileklihood for the celda Cell and Gene clustering model, given a set of cell / gene cluster assignments

calculateLoglikFromVariables.celda_CG(counts, sample.label, z, y, K, L, alpha,
  beta, delta, gamma)

Arguments

counts

Integer matrix. Rows represent features and columns represent cells.

sample.label

Vector or factor. Denotes the sample label for each cell (column) in the count matrix.

z

Numeric vector. Denotes cell population labels.

y

Numeric vector. Denotes feature module labels.

K

Integer. Number of cell populations.

L

Integer. Number of feature modules.

alpha

Numeric. Concentration parameter for Theta. Adds a pseudocount to each cell population in each sample. Default 1.

beta

Numeric. Concentration parameter for Phi. Adds a pseudocount to each feature module in each cell population. Default 1.

delta

Numeric. Concentration parameter for Psi. Adds a pseudocount to each feature in each module. Default 1.

gamma

Numeric. Concentration parameter for Eta. Adds a pseudocount to the number of features in each module. Default 1.

...

Additional parameters.

Examples

celda.sim = simulateCells(model="celda_CG") loglik = calculateLoglikFromVariables(celda.sim$counts, model="celda_CG", sample.label=celda.sim$sample.label, z=celda.sim$z, y=celda.sim$y, K=celda.sim$K, L=celda.sim$L, alpha=celda.sim$alpha, beta=celda.sim$beta, gamma=celda.sim$gamma, delta=celda.sim$delta)